Iran’s ICBM Program

Donald Trump tweeted that if he is assassinated by Iranian agents, “I hope that America obliterates Iran.” Tehran initiated an ICBM program shortly after he was elected (2020). It is expected to be operational in the near future (probably by January 2025, when the next POTUS is inaugurated. Would POTUS be willing to sacrifice cities on the American eastern seaboard if s/he launches a nuclear strike against Iran?